Opening Thoughts – My Zofran Story

Jan 1, 2016 | Home Birth Stories, On Motherhood | 16 comments

Well, what a difference five days makes. Have I got a story for you…

Firstly, thank you for all your kind words of love and support on my “Closing Thoughts” end of the year post earlier this week. I was touched by your sympathy and understanding.


I suffered from my severe (all day) morning sickness with my first two pregnancies and then with my third, well, by that point I had a new midwife, I found myself complaining to her one day about how horrible I felt and she said, “You know, there IS medication for that.”

WHAT? I was so mad. Not mad at her. But mad that I had suffered so much the first two times and no one had ever told me. (I mean, you’ve never lived till you’ve done your errands with a Target bag tied to the steering wheel so you could yack while you drive.)

I took her up on her kind offer and began taking the generic version of “Zofran”.

For me, little-miss-natural-pants this was a HUGE deal. I had tried everything… the stupid bracelets, ginger, saltines, gluten-free… every remedy that well-meaning people offer, I had tried… to no avail. So peeling back that little wrapper and taking a pharmaceutical was a big, desperate step for me.

Flash forward to the next pregnancies. I TRIED to avoid the Zofran. ‘Til one day my throat actually bled from irritation and I called my now beloved midwife and conceded, yet again.

So I took it for pregnancies three, four and five. Always the least amount I could. Always in desperation.

Well… this is my biggest gap in between pregnancies (a whopping three years). When that old black magic hit again I called my midwife for the “goods” only to be told that my miracle-fix had since been classified as a Class B drug known to cause birth defects (cleft palate, skull and heart).


But, she reassured me that there was something new that I could use. She gave me a sample. I struggled with taking it until one day it was so violent that I saw stars. I conceded yet again…  it took me a few days to ramp up to the full dose…

Nada. Not even a dent in my misery. To add insult to injury I got the flu and within nine hours ended up in the hospital for dehydration. I didn’t even mention that in my sob story the other day!

Well, I thought, “I can’t take something that could hurt my baby. I’m just gonna have to duke this one out.”

And that’s what I’ve been doing since mid-October. But slowly… as I wrote about the other day… slowly losing my mind.

I had my first midwife appointment on Tuesday. I was miserable. Just getting to her office took everything I had. I heard the baby’s strong heartbeat and that brought a momentary smile to my face. My sweet midwife could see my misery and said, “You know Ang… you’re past the birth defect stage in your baby’s development… if you wanted to go on the Zofran…” The thought of relief… I could hardly bear it…  but before I knew it I had to shove past my family and run down the hall to the bathroom. It was NOT pretty.

By that point, Joel and the kids were in the hall and he said, “That’s it.  I’m going back for that prescription.” My hero.

Two hours later I set the first tablet on my tongue to dissolve. Within FIFTEEN MINUTES I felt like myself again. I wept.


All those weeks of misery in a motherly effort to keep my little one safe. But I trust my midwife beyond measure. She is amazing. I have peace now. And a little package of generic Zofran. I’ve only been sick a few times this week, I’ve instead baked a cake for a friend, made 10 quarts of pasta sauce, made a New Year’s Eve meal for my family and enjoyed the company of my kids, I’ve even smiled.

Talk about a New Year, New You.

I know they’ll be more expectant mother stuff to deal with. No one gets out of it Scott-free. (I think my round ligaments are just going to SNAP this time based on how they are already freaking out on me!)

But praise the Lord I can stand upright, eat a meal and I’m not walking around feeling like I want to die.

I’m beginning today, 1/1/16 quiet and very grateful. I can’t really describe it.

Now… let’s get on with life!

Thanks for reading. Angela Parisienne Farmgirl



  1. Doré @ Burlap Luxe

    I read this and flash backs on how sick I was that I lost weight the first 6 months, I could not shake my sickness u till the end of 6 months, yes I tried everything, teas, tablets, ginger, you name it. It’s so nice to hear you have relief with the on going morning sickness, perhaps a bit more joy in your days will allow you to focus on more important planning and family needs.

    Keep up the good work and the beauty you create and inspire.



  2. Joannah

    I wonder when they realized it caused birth defects?! I was given Zofran (five years ago), but it made me so constipated that I didn’t take it much. I was given something else (prescription), and I remember taking Unisom because it helped with nausea.

    I’m glad you have some relief! Carry on, my friend. 🙂

  3. Patty

    I took Zofran for all of my pregnancies – with my twins I lost 15 pounds in one week from vomiting – it was a Godsend for me. I couldn’t even swallow my own saliva and was chronically dehydrated. Four kids and I was lucky to avoid birth defects. It was honestly about survival. People don’t realize how debilitating hyperemesis is. I so remember that feeling 15 minutes after taking a pill – sweet relief! I don’t know if I would have even made it to term with out it. So glad you are feeling better!

  4. Becca

    On round ligament pain. I had a midwife for baby #5, couldn’t face another hospital birth. I told her about all the struggles I’d had in the past with round ligament pain. She suggested 2 Tbs. liquid calcium magnesium (Tropical Oasis is the brand I still use nine years later.) AMAZING! Solved even more than just round ligament pain. Hope it offers you some relief, too.
    Happy to hear you’re feeling so much better!

    • Parisienne Farmgirl

      Really?!! Because I have already screamed out in pain a couple times and I’m not even big! They were so trashed after the last baby they hurt the last two years, not even being pregnant! I am going to look into this. Thank you so much!

  5. Cheryll

    Dear, dear Angela my thoughts and prayers are with you. Like you, I kept nothing down with first pregnancy. I weight less at the birth than I did at the beginning, from about 120 down to 109! I know, and I also had pneumonia in the 7th month. He was 8 lbs + and 21 inches long. He is now 6’4″ and 250 lbs and 43 years old. Second pregnancy same thing, he was 10 lbs and 20z but I stopped the vomiting by the 7th month. So, I do so understand. I decided to stop there. Couldn’t do it again.

    That said, I sure hope things settle down for you and yours and 2016 will bring another beautiful and healthy baby. ps, your book is on its way to me, can’t wait. Bless You.

  6. Kathleen Botsford

    You are and will always be my hero! With my first I threw up so violently my diamond necklace went down the loo!
    I also break all the blood vessels in my face every time I throw up. Keeping you and yours in my prayers

  7. Abby Jo

    I’m so glad you are better, was worried about you! You got do what you gotta do, your Husband is a hero! Good for him, taking care of his wife 🙂 Blessings on this pregnancy.

  8. Nan @ lbddiaries

    God will protect your precious baby and you. Thank God you have an awesome midwife. Remember God works through doctors and nurses and midwives – anything you need. The trust is in Him, not the meds or docs, nurses or midwives. I believe He will bring you through – NO MORE PUKING.

  9. Angela

    Oh my goodness! I am SO relieved you have found some help!

  10. Peggy Williams

    Just catching up on blogs and wanted to congratulate on your coming addition. Like you, I try to do everything as naturally as possible and do not like to use any meds. Been pretty proud of the fact my husband and I don’t take any, in fact. But this past November my husband, who is one the healthiest guys on the planet, had to have emergency surgery for a mass in his colon. Learned some stuff for sure. One is that colonoscopies are not just money makers for the medical profession because colon cancer can be a genetic tendency. His surgery went great because of his amazing health but right now (because they found cancer in 1 of 16 lymph nodes) he has to do chemo. Never thought this would be something we would face or do. But I have learned that drugs are sometimes really necessary! And being healthy is a bonus because it makes a huge difference in how you are able to cope with them. So glad you are feeling better and probably getting over all that by now or soon anyway. Love following you–you are always inspiring to me!

  11. Lori Barre

    So glad you are able to be you again. I had terrible morning (all day) sickness with my oldest daughter and again with my 3rd daughter. Not as terrible as you describe though.
    BTW, you look absolutely beautiful in the photo with the hat.
    Congratulations on another beautiful babe!!

  12. Susan Herring

    You have my heartfelt sympathy and understanding. I was sick the entire time with both of my babies. I remember waking up in the morning an thinking, “This is the best I’ll feel all day.”. After my first pregnancy a dentist looked at my teeth and asked if I was bulimic. I said, “no just pregnant.” He understood. Lots of love and prayers sending your way,

  13. Kristin

    I am sending you and your family lots of prayers! May God bless you with peace as you continue to submit to His will for your life. Though your children may not see a perfect mama, I pray they would see a woman striving through trials and difficulty to bring Him glory. I don’t know you but I feel certain that they are. Bless you.

  14. Alice

    At what point are you past the birth defect stage? My 22 yr old daughter is in total misery trying to get through her first trimester! She had mentioned Zofran to me, but I’m very concerned about when it’s considered safe.


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